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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP3
All Species:
20.61
Human Site:
S454
Identified Species:
56.67
UniProt:
P08254
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08254
NP_002413.1
477
53977
S454
F
Y
F
F
T
G
S
S
Q
L
E
F
D
P
N
Chimpanzee
Pan troglodytes
XP_508723
477
54030
S454
F
Y
F
F
T
G
S
S
Q
L
E
F
D
P
N
Rhesus Macaque
Macaca mulatta
XP_001098400
477
54003
S454
F
Y
F
F
T
G
S
S
Q
L
E
F
D
P
N
Dog
Lupus familis
XP_536598
470
53609
I447
I
Y
F
F
N
G
P
I
Q
F
E
Y
N
I
W
Cat
Felis silvestris
Mouse
Mus musculus
P28862
477
53827
S454
L
Y
F
F
S
G
S
S
Q
L
E
F
D
P
N
Rat
Rattus norvegicus
P03957
475
53409
S452
L
Y
F
F
S
G
S
S
Q
L
E
F
D
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508976
476
54530
Q453
F
Y
F
F
Q
G
S
Q
Q
L
Q
Y
E
P
S
Chicken
Gallus gallus
XP_417175
496
56924
N473
F
Y
F
F
H
G
S
N
Q
Y
E
V
D
I
K
Frog
Xenopus laevis
O13065
467
52794
S444
L
Y
F
F
I
G
R
S
Q
F
E
Y
N
I
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.7
50.7
N.A.
77.1
75
N.A.
56.5
53.6
50.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
97.4
67.7
N.A.
87
85.7
N.A.
72.3
66.5
66.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
40
N.A.
86.6
86.6
N.A.
60
60
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
93.3
93.3
N.A.
86.6
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
89
0
12
0
0
% E
% Phe:
56
0
100
100
0
0
0
0
0
23
0
56
0
0
0
% F
% Gly:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
12
0
0
12
0
0
0
0
0
34
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
34
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
12
0
0
0
0
23
0
67
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
0
0
0
67
0
% P
% Gln:
0
0
0
0
12
0
0
12
100
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
23
0
78
67
0
0
0
0
0
0
12
% S
% Thr:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% W
% Tyr:
0
100
0
0
0
0
0
0
0
12
0
34
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _